Research Directions
Pancreatitis
Pathogenesis, progression, and associated complications of acute pancreatitis.
Pancreatic Cancer
Molecular mechanisms and translational research in pancreatic cancer.
Clinical Bioinformatics
Mining clinical datasets to uncover mechanisms and predictors.
Funded Projects
PKC-ε/MLKL/BRD4 Axis Exacerbates Acute Pancreatitis-Associated Lung Injury by Inducing Alveolar Macrophage Pyroptosis via Exosomal S100A9
2025-01-01 to 2028-12-31, CNY 490,000, Host by Xiao Yu.
General Program of the National Natural Science Foundation of China (82472226).
IGF2BP3 Stabilizes S100A16 Expression to Induce Glutamine Metabolism Dysregulation and Promote Malignant Proliferation in Pancreatic Cancer
2023-01-01 to 2025-12-31, CNY 300,000, Host by Wenzhe Gao.
Young Scientists Fund of the National Natural Science Foundation of China (82203494).
IL-18 and IL-3 Synergistically Regulate the STAT3/IL-4 Pathway in Pancreatic Stellate Cells in Chronic Pancreatitis
2022-01-01 to 2024-12-31, CNY 300,000, Host by Zhiqiang Li.
Young Scientists Fund of the National Natural Science Foundation of China (82203494).
m6A Reader IGF2BP2 Mediates Autophagy via Stabilizing ULK1/Beclin-1 Signaling Axis to Promote Acute Pancreatitis Pathogenesis
2021-01-01 to 2023-12-31, CNY 240,000, Host by Hongwei Zhu.
Young Scientists Fund of the National Natural Science Foundation of China (82000614).
LncRNA MEG3/miR-21 Mediates Impaired Autophagic Flux through LAMP-2 to Trigger Necroptosis and Exacerbate Acute Pancreatitis
2019-01-01 to 2022-12-31, CNY 570,000, Host by Xiao Yu.
General Program of the National Natural Science Foundation of China (81873589).
mTORC2/CTGF Signaling Mediates Incretin Mimetics-Induced Chronic Pancreatic Fibrosis Injury
2016-01-01 to 2019-12-31, CNY 570,000, Host by Xiao Yu.
General Program of the National Natural Science Foundation of China (81570585).